Multicentre observational study describing the systemic response to small-area burns in children

Burns of less than 10% total body surface area (TBSA) are common injuries in children under five years age. The inflammatory response to burn injury is well recognised for burns greater 20% TBSA but has not been described smaller burns. aim this study was describe the systemic young with small-area Morbidity In Small Thermal Injury Children (MISTIC) a multicentre prospective observational cohort that recruited 625 patients age over eighteen months across three sites England. Prospectively collected data included physical observations and laboratory blood tests taken hospital as part routine care. Additional information sourced from temperature recordings at home following discharge. Elevated temperatures were observed scald or contact between 2–10% TBSA, peak on day one after followed by fall days four seven burn. No rise seen <2% TBSA. Higher readings associated larger size, two male sex. Heart rate C-Reactive Protein levels showed An identifiable reported. This knowledge can be used aid diagnosis who re-present pyrexia, no other symptoms indicate clinical infection.